An injured Syrian child receives treatment at a makeshift hospital on October 3, 2016, following reported air strikes in the rebel-held town of Douma, on the eastern outskirts of the capital Damascus.

One mother and her child have died after an aerial bomb targeted their home near Masaken Hanano neighbourhood in eastern Aleppo, according to human rights group.

At least 19 people were killed overnight according to the Syrian Obervatorty for Human Rights due to heavy shelling and regime forces advance to entrances of Masaken Hanano.

Clashes on Monday continued between regime forces and rebels backed by Fateh al-Sham around eastern Aleppo amid mutual bombardment from both sides. Aerial bombardments were focused on Ferdous and areas of Der Hafir, according to Syrian activists.

The situation has been dire for civilians as news confirmed that there were no more functioning hospitals in eastern Aleppo, where more than 250,000 people are currently living under siege and in need of urgent medical care according to the UN has said.

United States President Barack Obama confessed the crisis could persist for “quite some time”.

“I am not optimistic about the short-term prospects in Syria,” Obama said at a news conference in Lima at the conclusion of a summit with leaders of Pacific Rim countries.

UN agencies, including WHO, have been barred from entering eastern Aleppo since July when regime troops seized the last access route, leaving the area cut off from food and medical aid for more than four months.

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