Men rush away from a site hit by what activists said were airstrikes by forces loyal to Syria’s President Bashar al-Assad, in the Douma neighborhood of Damascus, Syria.

Syria’s army and rebels were locked in talks Wednesday night to reach a 15-day ceasefire in the Eastern Ghouta region east of the capital, a monitor and a security source told AFP.

These are the first known talks aiming for a truce in the region and are likely taking place with Russian or Iranian mediators, the Syrian Observatory for Human Rights said.

If agreement is reached, “a ceasefire in Eastern Ghouta would begin at 6:00 am (0400 GMT) Thursday and will last 15 days,” Observatory head Rami Abdel Rahman said.

A senior Syrian security source told AFP “talks are ongoing between the government and a number of armed groups in Eastern Ghouta… to stop military operations,” without giving further details.

“Our Russian allies are playing a direct role in contacting those that support the armed groups,” he said.

Jaish al-Islam, the most powerful rebel group in Eastern Ghouta, was the main negotiating partner on the rebel side, Abdel Rahman added.

A spokesman for the group could not be reached for comment.

Eastern Ghouta is the largest rebel stronghold near Damascus and is regularly bombarded by regime forces.

The talks come days after top diplomats from 17 countries met in Vienna to seek an end to Syria’s conflict, which has left more than 250,000 people dead since it erupted in 2011.

U.S. Secretary of State John Kerry said Tuesday Syria could be weeks away from a “big transition.”

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